Glossary · Clinical

MAT (Medication-Assisted Treatment)

MAT combines FDA-approved medications (methadone, buprenorphine, naltrexone) with counseling and behavioral therapies to treat substance use disorders. MAT is the evidence-based standard of care for opioid use disorder and is increasingly used for alcohol use disorder. EMRs supporting MAT must handle controlled-substance e-prescribing (EPCS) and integrate with state prescription drug monitoring programs.

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